Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men

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Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men

BACKGROUND Dietary supplements containing L-arginine are marketed to improve exercise performance, but the efficacy of such supplements is not clear. Therefore, this study examined the efficacy of acute ingestion of L-arginine alpha-ketoglutarate (AAKG) muscular strength and endurance in resistance trained and untrained men. METHODS Eight resistance trained and eight untrained healthy males i...

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Pharmacokinetics, safety, and effects on exercise performance of L-arginine alpha-ketoglutarate in trained adult men.

OBJECTIVE We evaluated the pharmacokinetics, safety, and efficacy of l-arginine alpha-ketoglutarate (AAKG) in trained adult men. METHODS Subjects participated in two studies that employed a randomized, double-blind, controlled design. In study 1, 10 healthy men (30-50 y old) fasted for 8 h and then ingested 4 g of time-released or non-timed-released AAKG. Blood samples were taken for 8 h afte...

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Acute arginine supplementation fails to improve muscle endurance or affect blood pressure responses to resistance training.

Dietary supplement companies claim that arginine supplements acutely enhance skeletal muscular endurance. The purpose of this study was to determine whether acute arginine α-ketoglutarate supplementation (AAKG) will affect local muscle endurance of the arm and shoulder girdle or the blood pressure (BP) response to anaerobic exercise. Twelve trained college-aged men (22.6 ± 3.8 years) performed ...

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Effects of 7 days of arginine-alpha-ketoglutarate supplementation on blood flow, plasma L-arginine, nitric oxide metabolites, and asymmetric dimethyl arginine after resistance exercise.

BACKGROUND Arginine-alpha-ketoglutarate (AAKG) supplements are alleged to increase nitric oxide production, thereby resulting in vasodilation during resistance exercise. This study sought to determine the effects of AAKG supplementation on hemodynamics and brachial-artery blood flow and the circulating levels of L-arginine, nitric oxide metabolites (NOx; nitrate/nitrite), asymmetric dimethyl ar...

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Four weeks of supplementation with a multi-nutrient product increases lean mass and muscular performance in resistance trained men

Methods Using a randomized, double-blind design, 30 healthy men (mean ± SD age, height, weight, % body fat: 25.7 ± 6.7 y, 178.0 ± 6.4 cm, 84.4 ± 10.7 kg, 18.9 ± 7.0%) were matched for age, resistance training history, daily caffeine intake, weekly meat consumption, bench press strength, bench press endurance, and percent body fat and then randomly assigned to ingest 2–3 scoops per day of SP250 ...

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ژورنال

عنوان ژورنال: Journal of the International Society of Sports Nutrition

سال: 2012

ISSN: 1550-2783

DOI: 10.1186/1550-2783-9-17